AROGYA

AROGYA: Healthy Aging with HIV

Healthy aging with HIV has become an increasingly relevant and achievable goal, thanks to advancements in medical care and antiretroviral therapies. As individuals with HIV live longer, the focus has shifted to promoting overall well-being and addressing age-related health concerns. Comprehensive healthcare strategies now emphasize controlling the virus and managing other health factors, such as cardiovascular health, bone density, mental health, and social well-being.

The application of interdisciplinary science, specifically the integration of multi-omics systems biology and advanced technology like organ-on-chip, holds immense promise in understanding and promoting healthy aging. To explore the intricate molecular mechanisms underlying the aging process at a systemic level, we use multi-omics systems biology that involves the comprehensive analysis of various biological data sets, such as transcriptomics, proteomics, metabolomics, microbiome, and more, from well-defined clinical cohorts from both high and low-income

Figure: The concept of the AROGYA project